We look back at one of the most popular CPAP devices of its time, covering its core features, pros and cons, and exploring the best modern alternatives.
Philips Respironics System One: Review & Price
One of the most sold out CPAP machines in the US market historically, the Philips Respironics System One CPAP is a popular sleep apnea device with a huge market share. Today we will look into what made that machine the bestseller it was, while providing a brief review of the Philips System One pros and cons. Hold tight, this is going to be short, but epic!
What is Philips Respironics System One?
System One is a standard CPAP (Continuous Positive Airway Pressure) device boasting effective and comfortable sleep apnoea therapy at home. Among the main benefits of this Philips device is the simple, user-friendly, and quiet operation. The device features an advanced apnea-detection system monitoring the apnea-hypopnea index through the night, as well as leak events, flow and respiratory effort-related arousals (RERAs), which comes in handy for sleep specialists keeping track of ongoing therapy.
This CPAP is also rather portable (although not specifically a dedicated ‘travel cpap‘) and is easy to take along in carry-on luggage.

Pros & Cons
✓ Pros
The Philips Respironics System One is primarily designed with natural sleep in mind, giving the user a simple and easy-to-understand interface and settings. One of its main pros is its quiet operation and lightweight main body. Humidification options are also available with this Respironics series made and assembled in the USA.
✗ Cons
It is not as advanced as some of the latest machines, like the AirSense 11, which are tailored to specific therapy types and patients. In addition, to achieve a full seal, the user often needed the proprietary Philips ComfortGel Blue mask, which is redundant in other leading CPAPs. The biggest con? It is discontinued. You cannot order the Philips Respironics System One anymore — at least not from CPAP retailers in Europe and the USA.
How does the System One CPAP perform?
The overall performance of this device is more than satisfactory as it manages to provide the sleeper with a steady, gentle flow of air as per the prescribed therapy pressure. If you’re looking for a reliable CPAP device to keep your airways open, this will do the trick. Add to that the included comfort features such as the Philips C-Flex algorithm, and your needs will be met.
System One Auto CPAP Devices

The System One auto CPAP version is called REMstar and delivers a gradual pressure transition from inhalation to exhalation in order to maintain maximum comfort through the night. As its name suggests, this machine will automatically adjust the airflow to respond to your apneic events and prevent the debilitating obstruction typical of OSA. Another important difference is that the auto model can use up about 35-40% less pressure than the standard one.
System One Bi-level Devices
In addition to its standard CPAP line, the Respironics System One was also available in a BiPAP version. The BiPAP model delivers two positive pressure levels, including IPAP (Inspiratory Positive Airway Pressure) and EPAP (Expiratory Positive Airway Pressure). The BiPAP version is designed for users whose doctors have prescribed it, offering a more comfortable therapy through better-adjusted ramp times to help you fall asleep faster.

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Frequently Asked Questions & Specs
Does the Respironics System One come with a humidifier?
Is the Philips Respironics System One available for purchase?
Where can you buy a Respironics System One?
How much does the Philips Respironics System One cost?
I live in Europe. Can I order Respironics System One here?
What are the full System One specifications?
- Enhanced performance and user comfort
- Advanced humidification system utilizing different sensors (Dry Box technology)
- C-Flex pressure relief technology for added comfort
- Very Quiet CPAP for its class
- 3 different ‘Smart’ operating modes (including Straight CPAP mode)
- Proprietary Mask Fit technology
- Advanced OSA detection and intuitive reporting
Confer with the full Respironics System One User Manual here.
Looking to Upgrade?
Browse our quick categories to find exactly what you need for your sleep apnea therapy:
Shop Standard CPAPs • Shop Auto CPAPs • Shop BiPAPs • Shop Masks
Please note: Choosing a CPAP machine is a personal medical decision. Since the Philips Respironics System One is discontinued, you should consult your doctor or sleep specialist to determine which specific modern device and therapy mode is the best replacement for your individual needs and condition.